Characteristics of gastrointestinal stromal tumors associated to other tumors: Características de los tumores del estroma gastrointestinal asociados a otras neoplasias.

INTRODUCTION: Our aim is to analyze the differences between sporadic gastrointestinal stromal tumors and those associated with other tumors. METHODS: Retrospective cohort study including patients with diagnosis of gastrointestinal stromal tumors operated at our center. Patients were divided into two groups, according to whether or not they had associated other tumors, both synchronously and metachronously. Disease free survival and overall survival were calculated for both groups. RESULTS: 96 patients were included, 60 (62.5%) were male, with a median age of 66.8 (35-84). An association with other tumors was found in 33 cases (34.3%); 12 were synchronous (36.3%) and 21 metachronous (63.7%). The presence of mutations in associated tumors was 70% and in non-associated tumors 75%. Associated tumors were classified as low risk tumors based on Fletcher's stratification scale (p = 0.001) as they usually were smaller in size and had less than ≤5 mitosis per 50 HPF compared to non-associated tumors. When analyzing overall survival, there were statistically significant differences (p = 0,035) between both groups. CONCLUSION: The relatively high proportion of gastrointestinal stromal tumors cases with associated tumors suggests the need to carry out a study to rule out presence of a second neoplasm and a long-term follow-up should be carried out in order to diagnose a possible second neoplasm. Gastrointestinal stromal tumors associated with other tumors have usually low risk of recurrence with a good long-term prognosis.

Manejo diagnóstico y terapéutico de la filariasis mamaria / Diagnostic and therapeutic management to breast filariasis

La filariasis es una enfermedad parasitaria benigna poco frecuente en los países occidentales, sobre todo la afectación mamaria es inusual. Sin embargo, aumenta la frecuencia de casos de filariasis mamaria en nuestro medio debido a las corrientes migratorias y el turismo a zonas endémicas. Nuestro objetivo es incidir en el manejo diagnóstico y terapéutico de la filariasis mamaria a propósito de un caso clínico

Filariasis is a benign parasitic disease that is unusual in western countries, especially filariasis of the breast. However, cases of breast filariasis are increasing in our environment due to greater immigration and tourism to endemic areas. We report a case of breast filariasis to describe the diagnostic and therapeutic management of this disease